くすりのしおり

Internal
Published: 2/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Spironolactone Tablets 25mg "Nichiiko"
 Active ingredient:
Spironolactone
 Dosage form:
white to slightly yellowish white tablet, diameter 9.0mm, thickness 4.4mm
 Print on wrapping:
スピロノラクトン錠25mg「日医工」,n116,スピロノラクトン,25,NICHI-IKO,Spironolactone tab.25mg,スピロノラクトン「日医工」,25mg

Effects of this medicine

This medicine promotes sodium/water excretion and supresses potassium excretion in the kidney to increase the urine volume. This will eliminate extra body fluid, lower blood pressure and reduce body swelling.
It is usually used to treat the hypertension, cardiac edema(congestive heart failure), hepatic edema, renal edema etc. It is also used for the diagnosis and improvement of the symptoms in primary aldosteronism.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have anuria, acute renal failure, hyperkalemia and Addison's disease.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 to 4 tablets (50 to 100mg of the active ingredient) a day, in divided doses. The dosage may be adjusted according to disease, age and symptoms of the patient. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness etc. due to decreased blood pressure. Be aware of operating in potentially hazardous activities such as driving a car and working at heights.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, hives, malaise, itch and gynecomastia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • arrhythmia, general malaise, weakness [electrolyte abnormality(hyperkalemia, hyponatremia, metabolic acidosis etc.)]
  • decreased urine output, swelling of extremities and face, general malaise [acute renal failure]
  • high fever, bloodshot eyes, erythema  [toxic epidermal necrolysis, mucocutaneous-ocular syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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