くすりのしおり

Internal
Revised: 11/2017

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Retrovir Capsules 100mg
 Active ingredient:
Zidovudine
 Dosage form:
white (opaque)/white (opaque) capsule
 Print on wrapping:
GSYJU

Effects of this medicine

This medicine suppresses the progression of diseases such as decreased immune function, decreased body weight, swollen lymph node and opportunistic infection by inhibiting the activity of HIV-1 reverse transcriptase and subsequently suppressing the growth of human immunodeficiency viruses (HIVs).
It is usually used to treat HIV infection in combination with other anti-HIV drugs.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 5 to 6 capsules (500 to 600 mg of the active ingredient) a day, in 2 to 6 divided doses. The dosage may be reduced according to the symptoms. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so. If you stop taking this medicine only because your subjective symptoms have disappeared, your condition may deteriorate.

Precautions while taking this medicine

  • It is important that you receive medical examination on a regular basis to check on the appropriateness of the dosage and any side effect that may have occurred without your noticing.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include anemia, nausea, loss of appetite, abdominal pain and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, fever, bleeding symptoms (nose/gum bleeding, subcutaneous bleeding of limbs) [aplastic anemia, pure red cell aplasia, pancytopenia, anemia, decreased white blood cells, decreased neutrophils, decreased platelets]
  • general edema, respiratory distress, fatiguability [congestive heart failure]
  • hyperventilation, consciousness disorder, shivering of limbs [severe liver enlargement due to lactic acidosis and adiposis (fatty liver)]
  • stiffness or shivering of systemic or local muscle, consciousness disorder, retrograde amnesia (loss of consciousness before a seizure) [epileptiform attack]
  • severe upper abdominal pain, lumbar/back pain, fever [pancreatitis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Seek advice of your pharmacy or medical institution about proper disposal of the unused medicines.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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