くすりのしおり

Internal
Revised: 6/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
PONTAL POWDER 50%
 Active ingredient:
Mefenamic acid
 Dosage form:
powder (white to faintly yellowish white)
 Print on wrapping:

Effects of this medicine

This medicine suppresses prostaglandin synthesis in order to ease swelling/pain induced by inflammation as well as to relieve the fever.
It is usually used for analgetic/anti-inflammatory purposes after surgery/wounds, to relieve inflammation/pain/fever caused by osteoarthritis/lumbar pain/symptomatic neuralgia/headache, or to relieve the fever/pain associated with acute upper respiratory tract infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: peptic ulcer, blood abnormality, liver dysfunction, kidney dysfunction, cardiac function failure, hypertension, aspirin asthma or its history.
    If you are a pediatric (child) patient with flu-induced fever.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • To relieve inflammation/swelling induced after surgery/wounds, and to relieve inflammation/pain/fever caused by osteoarthritis, lumbar pain, symptomatic neuralgia, headache (when other medicines did not work), sinusitis, menstrual pain, pain after delivery and tooth pain: In general, for adults, take 1 g (500 mg of the active ingredient) at a time at first, and follow with taking 0.5 g (250 mg) every 6 hours. The dose may be adjusted according to your age and symptoms.
    To relieve the fever/pain associated with acute upper respiratory tract infection (including that accompanied by acute bronchitis): In general, for adults, take 1 g (500 mg of the active ingredient) at a time, as needed. For children, the standard dose is 6.5 mg/kg of the active ingredient at a time, as needed. The dose may be adjusted according to your age and symptoms. Usually up to twice a day. Adults should not take more than 3 g (1,500 mg) a day.
    Avoid taking the medicine on an empty stomach in any case. 1 g of this medicine contains 500 mg of the active ingredient. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause sleepiness and dizziness. Pay attention when you drive a car, operate dangerous machinery while you take it.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include gastrointestinal disorder, nausea, diarrhea/ loose stool, rash, thrombocytopenic purpura, hives, redness, itch, and blood vomiting. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • cold sweat, breathing difficulty, numbness in the limbs [shock, anaphylaxis]
  • anemia, headache, sore throat, high fever with chills/tremor [hemolytic anemia, agranulocytosis]
  • palpitation, dizziness, bleeding tendency [bone marrow aplasia]
  • fever, redness/blister of skin/mucous membrane, sore throat  [toxic epidermal necrosis, oculomucocutaneous syndrome]
  • decreased urine output, edema, loss of appetite [acute kidney injury, nephrotic syndrome, interstitial nephritis]
  • pain in the pit of the stomach, tenderness, vomiting, diarrhea [peptic ulcer, colitis]
  • general malaise, loss of appetite, yellowing of the skin/white of eyes [fulminant hepatitis, liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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