くすりのしおり

Internal
Revised: 2/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
STOCRIN Tablets 200mg
 Active ingredient:
Efavirenz
 Dosage form:
yellow tablet (diameter: 11.1 mm, thickness 4.3 mm)
 Print on wrapping:
223

Effects of this medicine

This medicine suppresses viral reproduction of the human immunodeficiency virus (HIV), which depresses the immune system of the body and produces opportunistic infections, by competitively inhibiting reverse transcriptase in the virus, and shows antiviral action.
It is usually used in the treatment of HIV infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reaction (itch, rash etc.) to any medicine.
    If you have: hepatic disorder, history or suspected of hepatitis B or C.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 3 tablets (600 mg of the active ingredient) at a time, once daily, concurrently with other anti-HIV medicine. It would be okay whether you take the medicine with food or not, however, it is recommended to take on an empty stomach or before bedtime to avoid developing adverse reactions. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as possible when you remembered that you missed a dose. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • The medicine may cause dizziness, decline of concentration, or drowsiness. Avoid driving a car or operating dangerous machinery after taking the medicine.
  • Please note that alcohol may enhance the effect of the medicine.
  • Please note that foods containing Saint John's wort may stimulate metabolism of the medicine and diminish the effect.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, nausea, dizziness, diarrhea, headache, insomnia, fatigue and impairment of concentration. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, stomatitis, skin erythema, blister [Stevens-Johnson syndrome, erythema multiforme]
  • loss of appetite, nausea, vomiting, hand tremor flapping [hepatic failure]
  • palpitation, loss of consciousness [QT prolongation (abnormal electrocardiogram)]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep the medicine out of the reach of children. Store it away from direct sunlight, heat and moisture.
  • Do not store the remainder and ask your pharmacist or medical institutions how to discard it.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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