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Eisai Co., Ltd.
Internal
Revised: 9/2014
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LYRICA Capsules 150mg
Active ingredient:
Pregabalin
Dosage form:
white/ white capsule, diameter : 6.4 mm, length : 18.0 mm
Print on wrapping:
リリカ150mg, LYRICA150mg, PGN150
Effects of this medicine
This medicine inhibits calcium influx and suppresses release of excitatory neurotransmitters such as glutamic acid
in the central nervous system to tranquilize over-excited nerves and relieve pain.
It is usually used for treatment of neuropathic pain and pain associated with fibromyalgia.
Before using this medicine, be sure to tell your doctor and pharmacist
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: kidney dysfunction, congestive heart failure or a history of angioedema.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is
(( to be written by a healthcare professional))
Neuropathic pain
: In general, for adults, as an initial dose, take 75 mg of the active ingredient at a time, twice
a day, and then the daily dosage is gradually increased up to 300 mg in a week or more. The dosage may be
adjusted according to the age or symptoms. However, the maximum daily dosage is 600 mg in two divided
doses.
Pain associated with fibromyalgia
: In general, for adults, as an initial dose, take 75 mg of the active ingredient
at a time, twice a day. The daily dosage is gradually increased up to 300 mg in a week or more and will be
maintained at 300 to 450 mg. The dosage may be adjusted according to the age or symptoms. However, the
maximum daily dosage is 450 mg in two divided doses.
This preparation contains 150 mg of the active ingredient in a capsule. Strictly follow the instructions in either
case.
If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the
missed dose and follow your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking the medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
This medicine may cause dizziness, somnolence or loss of consciousness and there is a case resulted in car
accident. Avoid performing dangerous operations such as driving a car while taking this medicine. Especially, if
you are an elderly adult, special caution should be taken because there is a case resulted in falling and fracture
due to these symptoms.
This medicine may cause weight gain. Consult with your doctor or pharmacist if a sign of obesity occurs.
This medicine may cause double vision and blurred vision. Consult with your doctor or pharmacist if any of
them occurs.
Pay attention to the fact that drinking alcohol may intensify the effect of the medicine.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include dizziness, somnolence, edema and weight gain. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
light headedness, absent-minded/nearly sleeping situation, loss of consciousness [dizziness, somnolence, unconsciousness]
respiratory distress, general edema, palpitation upon exertion [heart failure, pulmonary edema]
muscle pain, lassitude, red urine [rhabdomyolysis]
decrease of urine output, swelling of the limbs and face, malaise [kidney failure]
swelling of the face/tongue/lips/throat, hives, respiratory distress [angioedema, shock, anaphylaxis]
lassitude, malaise, cold sweat [hypoglycaemia]
dry cough, respiratory distress, fever [interstitial pneumonia]
high fever, bloodshot eyes, red rash [Stevens-Johnson syndrome, erythema multiforme]
loss of appetite/nausea/vomiting, general malaise, jaundice, itch [fulminant hepatitis, liver disfunction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
Discard the remainder. Do not store them.
For healthcare professional use only :
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