くすりのしおり

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Revised: 11/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
REFLAP Ointment 5%
 Active ingredient:
Lysozyme hydrochloride
 Dosage form:
white to yellowish white ointment
 Print on wrapping:
リフラップ軟膏5%

Effects of this medicine

This medicine is an enzyme breaking down protein or mucus. It stimulates the proliferation of fibroblasts and hastens would healing.
It is usually used in the treatment of skin ulcer such as decubitus, burn ulcer, traumatic ulcer.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rach, etc.) to any medicines.
    If you have any allergic disposition such as egg-white allergy, atopic dermatitis, bronchial asthma, food allergy.
    If your parents or siblings are predisposed to allergies.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, apply an appropriate amount (according to your symptom or the size of focus) by plastering gauze with medicine or applying directly to the affected area, once to several times a day, after wiping cleanly affected area. Strictly follow the instructions.
  • Do not apply the medicine to the eye.
  • If you miss a dose, plaster or apply a dose as soon as possible.
  • If you accidentally use more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop using this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include erythema, redness, blister and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • urticaria, hypotension, lowering of conciousness  [shock, anaphylactoid symptoms]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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