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海外渡航情報
DAIICHI SANKYO COMPANY, LIMITED
Internal
Revised: 2/2015
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ISCOTIN TABLETS 100mg
Active ingredient:
Isoniazid
Dosage form:
white tablet with a split line (diameter:8.8 mm, thickness:3.4 mm)
Print on wrapping:
イスコチン錠100,D702
Effects of this medicine
This medicine is a chemotherapeutic agent and shows antibacterial effect by inhibiting proliferation of Mycobacterium tuberculosis. It is usually used to treat pulmonary tuberculosis and other tuberculosis.
Before using this medicine, be sure to tell your doctor and pharmacist
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: hepatic disorder, renal disorder, psychiatric disorder, alcohol intoxication, convulsive disorders including epilepsy, drug hypersensitivity, blood disorder or bleeding tendency.
If you are pregnant or breastfeeding
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is
(( to be written by a healthcare professional))
In general, for adults, take 2 to 5 tablets (200 to 500 mg of the active ingredient) daily, in 1 to 3 divided doses, every day or two days a week. When needed, the daily dose is increased up to 10 tablets in adults, 20 mg/kg in children younger than 13 years. The dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
If you missed a dose, take a dose as soon as possible when you remember that you missed a dose. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
If you accidentally took more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
Please note that eating fish which contains large amounts of histidine (tuna etc.) may cause headache, erythema, vomiting and itchiness, and eating food which contains large amounts of tyramine (cheese etc.) may cause increase in blood pressure and palpitation while you are taking the medicine.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include bleeding tendency, headache, dizziness, malaise, loss of appetite, nausea, vomiting, stomach distension, abdominal pain and constipation. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
loss of appetite, general malaise, yellowing of the skin/white of eyes [serious liver disorder including hepatitis fulminant]
fever, erythema, blister, erosion [toxic epidermal necrosis, Stevens-Johnson syndrome, erythroderma (exfoliative dermatitis)]
rash, fever [drug-induced hypersensitivity syndrome]
fever, erythema, muscle ache, joint ache [systemic lupus erythematosus symptoms]
fever, dry cough, breathing difficulty [interstitial pneumonia]
fever, rash, decrease of urine output, swelling of the limbs and face [renal failure, interstitial nephritis, nephrotic syndrome]
fever, sore throat, general malaise, bleeding tendency (gums bleeding, nasal bleeding, subcutaneous hemorrhage, etc.) [agranulocytosis, thrombocytopenia]
paroxysmal muscular cramp [convulsion]
visual impairment, blurred vision (decreased vision in central field) [optic neuritis, optic atrophy]
abnormal sensation in the limbs, numbness, sensory abnormality [peripheral neuritis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep the medicine out of the reach of children. Store it away from light, heat, and moisture.
Discard the remainder. Do not store them.
For healthcare professional use only :
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For further information, talk to your doctor or pharmacist.
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