くすりのしおり

Internal
Revised: 4/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ALEVIATIN Tablets 100mg
 Active ingredient:
Phenytoin
 Dosage form:
white tablet (diameter: 9 mm, thickness: 3.4 mm)
 Print on wrapping:
(face) アレビアチン 100 mg, アレビアチン, 100mg, P172
(bacck) ALEVIATIN 100 mg, アレビアチン, 100mg

Effects of this medicine

This medicine works on central nervous system in order to control epilepsy seizure.
It is usually used to treat convulsive/autonomic/psychomotor seizure caused by epilepsy.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, take 200 to 300mg of the active ingredient a day for adults, 100 to 300mg of the active ingredient a day for schoolchildren, 50 to 200mg of the active ingredient a day for young children and 20 to 100mg of the active ingredient a day for babies, in 3 divided doses a day, after each meal, respectively. The dose may be adjusted according to patient's symptoms and tolerance to the medicine. 1 tablet contains 100mg of the active ingredient. Strictly follow the instructions of your doctor and pharmacist.
  • If you miss a dose, take the missed dose as soon as possible. However, you have to wait about 4 hours before the next dose. If it is almost time for the next dose, skip the missed dose and consult your doctor. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause sleepiness, diminished attention, loss of concentration, decreased reflex motor capacity, etc. Therefore do not drive a car or operate dangerous machinery while taking it.
  • Do not take St. John's Wort-containing food since it may reduce the effect of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include systemic red rash, headache, nervous irritability, double vision, gingival enlargement, osteomalacia (pain when walking) and hairiness. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, rash/blister in skin, bloodshot eyes, erosion in lips/mouth [toxic epidermal necrosis, mucocutaneous ocular syndrome]
  • fever, joint pain, facial erythema, easy fatigability [SLE (systemic lupus erythematosus) like symptoms]
  • rash, fever, lymph node swelling [hypersensitivity syndrome]
  • anemic condition, generalized fatigability, sore throat  [aplastic anemia, pancytopenia, agranulocytosis, monocytic leukemia, thrombocytopenia, hemolytic anemia, pure red cell aplasia]
  • generalized fatigability, loss of appetite, yellowness in the skin and the conjunctiva [fulminant hepatitis, liver dysfunction, jaundice]
  • fever, dry cough, breathing difficulty [interstitial pneumonia]
  • sudden fever, muscle rigidity, hands/feet tremor [malignant syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from heat, moisture and direct sunlight.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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