くすりのしおり

Internal
Revised: 2/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
EVOXAC CAPSULES 30mg
 Active ingredient:
Cevimeline hydrochloride hydrate
 Dosage form:
yellow/white capsule (major axis: 16 mm)
 Print on wrapping:
Evoxac 30mg,エボザック30mg

Effects of this medicine

This medicine stimulates muscarinic receptors on the salivary gland, and promotes salivation.
It is usually used for improvement of oral dryness in the patients with Sjogren's syndrome.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you ever experienced any allergic reaction (itch, rash, etc.) to any medicine.
    If you are a patient with ischemic heart disease (myocardial infarction, angina pectoris, etc.), bronchial asthma, chronic obstructive pulmonary disease, gastrointestinal obstruction, urinary bladder neck obstruction, epilepsy, Parkinsonian syndrome, Parkinson's disease, or iritis.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take one capsule (30 mg of the active ingredient) at a time, 3 times daily, after meals. Strictly follow the instructions of your doctor/pharmacist.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
  • If you took too much of the medicine (more than prescribed), check with your doctor/pharmacist.
  • Do not stop taking the medicine without the instructions of your doctor.

Precautions while taking this medicine

  • The medicine may cause miosis. Pay close attention when you drive a car during the evening, or operate dangerous machinery in a dark place.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, abdominal pain, diarrhea, vomiting, loss of appetite, salivary gland pain, salivary gland hypertrophy, palpitation, frequent urination, hyperhidrosis, headache, chest pain, malaise, etc. If any of these symptoms occur,check with your doctor/pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever, dry cough, breathing difficulty  [exacerbation of interstitial pneumonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep the medicine out of the reach of children. Store it away from direct sunlight, heat and moisture (this medicine is hygroscopic).
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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