くすりのしおり

Internal
Revised: 12/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BEPRICOR TABLETS 50mg
 Active ingredient:
Bepridil hydrochloride hydrate
 Dosage form:
white to faintly yellowish white tablet, diameter: 6.1 mm, thickness: 2.9 mm
 Print on wrapping:
ZT1, ベプリコール50mg, Bepricor 50mg

Effects of this medicine

This medicine improves the symptoms of sustained atrial fibrillation and tachyarrhythmia (with vigorous contraction of heart muscle) by suppressing the abnormal contraction of heart muscle. It also improves angina symptoms by stretching vessels to increase blood circulation.
It is usually used to treat sustained atrial fibrillation, tachyarrhythmia (ventricular) and angina.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc. ) to any medicines.
    If you have: congestive heart failure, electrocardiogram abnormality or sinus bradycardia (slowing of the heart rate ).
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Sustained atrial fibrillation: In general, for adults, take 2 tablets (100 mg of the active ingredient ) at a time, twice a day. If the effect is insufficient, take 4 tablets (200 mg ) at a time, twice a day. The dose may be decreased according to your age and symptoms.
    Tachyarrhythmia (ventricular) and angina
    : In general, for adults, take 2 tablets (100 mg ) at a time, twice a day. The dose may be adjusted according to your disease, age and symptoms.
    In either cases, strictly follow the instructions of your doctor and pharmacist.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness. Pay attention when you operate dangerous machinery such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, rash, palpitation, headache and fatigue. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • palpitation, dizziness, syncope [QT prolonged, ventricular tachycardia, ventricular fibrillation, sinus arrest, atrioventricular block]
  • fever, diarrhea, general fatigue [agranulocytosis]
  • fever, dry cough, respiratory distress [interstitial pneumonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacist how to discard.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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